PROPYLENE GLYCOL
MSDS Number: P6928 --- Effective
Date: 11/02/06
1. Product
Identification
Synonyms: 1,2-propanediol; 1,2-dihdroxypropane; methyl glycol; methylethylene glycol
CAS No.: 57-55-6
Molecular Weight: 76.09
Chemical Formula: CH3CHOHCH2OH
Product Codes: J.T. Baker: 9402, 9403, U510
Mallinckrodt: 1925, 6263
2.
Composition/Information on Ingredients
Ingredient
CAS No Percent Hazardous
---------------------------------------
------------ ------------ ---------
Propylene Glycol
57-55-6 99 - 100% Yes
3. Hazards
Identification
Emergency Overview
--------------------------
CAUTION! MAY CAUSE IRRITATION TO SKIN AND EYES.
J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your
convenience)
-----------------------------------------------------------------------------------------------------------
Health Rating: 0 - None
Flammability Rating: 1 - Slight
Reactivity Rating: 1 - Slight
Contact Rating: 1 - Slight
Lab Protective Equip: GOGGLES; LAB COAT
Storage Color Code: Orange (General Storage)
-----------------------------------------------------------------------------------------------------------
Potential Health Effects
----------------------------------
Inhalation:
No adverse health effects via inhalation.
Ingestion:
Relatively non-toxic. Ingestion of sizable amount (over 100ml) may cause some
gastrointestinal upset and temporary central nervous system depression. Effects
appear more severe in individuals with kidney problems.
Skin Contact:
Mild irritant and defatting agent, especially on
prolonged contact.
Eye Contact:
May cause transitory stinging and tearing.
Chronic Exposure:
Lactic acidosis, stupor and seizures have been reported following chronic
ingestion.
Aggravation of Pre-existing Conditions:
Kidney disorders.
4. First Aid Measures
Inhalation:
Remove to fresh air. Not expected to require first aid measures.
Ingestion:
Not expected to require first aid measures. Give several glasses of water to
drink to dilute. If large amounts were swallowed, get medical advice.
Skin Contact:
Remove any contaminated clothing. Wash skin with soap and water for at least 15
minutes. Get medical attention if irritation develops or persists.
Eye Contact:
In case of contact, immediately flush eyes with plenty of water for at least 15
minutes, lifting upper and lower eyelids occasionally. Call a physician if
irritation persists.
Note to Physician:
In case of ingestion, monitor for acidosis and central nervous system changes.
Exposed persons with previous kidney dysfunction may require special treatment.
5. Fire Fighting
Measures
Fire:
Flash point: 99C (210F) CC
Autoignition temperature: 371C (700F)
Flammable limits in air % by volume:
lel: 2.6; uel: 12.5
Material can support combustion.
Explosion:
Containers may explode in heat or fire.
Fire Extinguishing Media:
Dry chemical, foam, water or carbon dioxide.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved
self-contained breathing apparatus with full facepiece
operated in the pressure demand or other positive pressure mode. Move exposed
containers from fire area, if it can be done without risk. Use water to keep
fire-exposed containers cool.
6. Accidental Release
Measures
Ventilate
area of leak or spill. Remove all sources of ignition. Wear appropriate
personal protective equipment as specified in Section 8. Isolate hazard area.
Keep unnecessary and unprotected personnel from entering. Contain and recover
liquid when possible. Use non-sparking tools and equipment. Collect liquid in
an appropriate container or absorb with an inert material (e. g., vermiculite,
dry sand, earth), and place in a chemical waste container. Do not use
combustible materials, such as saw dust. Do not flush to sewer!
7. Handling and Storage
Protect container from
physical damage. Store in a cool, dry, ventilated area away from sources of
heat, moisture, and incompatible substances. Containers of this material may be
hazardous when empty since they retain product residues (vapors, liquid); observe
all warnings and precautions listed for the product.
8. Exposure
Controls/Personal Protection
Airborne Exposure Limits:
AIHA Workplace Environmental Exposure Level (WEEL): Vapor and Aerosol = 50ppm;
Aerosol, only = 10mg/m3.
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee
exposures below the Airborne Exposure Limits. Local exhaust ventilation is
generally preferred because it can control the emissions of the contaminant at
its source, preventing dispersion of it into the general work area. Please
refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended
Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded, a half-face respirator with an organic vapor
cartridge and particulate filter (NIOSH type P95 or R95 filter) may be worn for
up to ten times the exposure limit or the maximum use concentration specified
by the appropriate regulatory agency or respirator supplier, whichever is
lowest. A full-face piece respirator with an organic vapor cartridge and
particulate filter (NIOSH P100 or R100 filter) may be worn up to 50 times the
exposure limit, or the maximum use concentration specified by the appropriate
regulatory agency or respirator supplier, whichever is lowest. Please note that
N series filters are not recommended for this material. For emergencies or
instances where the exposure levels are not known, use a full-face piece
positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators
do not protect workers in oxygen-deficient atmospheres.
Skin Protection:
Wear protective gloves and clean body-covering clothing.
Eye Protection:
Use chemical safety goggles. Maintain eye wash fountain and quick-drench facilities
in work area.
9. Physical and Chemical
Properties
Appearance:
Clear oily liquid.
Odor:
Odorless.
Solubility:
Miscible in water.
Specific Gravity:
1.0361 @ 20C/4C
pH:
No information found.
% Volatiles by volume @ 21C (70F):
No information found.
Boiling Point:
188.2C (370F)
Melting Point:
-59C (-74F)
Vapor Density (Air=1):
2.6
Vapor Pressure (mm Hg):
0.129 @ 25C (77F)
Evaporation Rate (BuAc=1):
0.01
10. Stability and
Reactivity
Stability:
Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products:
Carbon dioxide and carbon monoxide may form when heated to decomposition. Aldehydes or lactic, pyruvic or
acetic acids may also be formed.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Strong oxidizing agents.
Conditions to Avoid:
Heat, flames, ignition sources and incompatibles.
11. Toxicological
Information
Oral rat LD50: 20g/kg. Skin rabbit LD50: 20.8g/kg.
Irritation: Eye rabbit/Draize, 500 mg/24H mild.
Investigated as a mutagen and reproductive effector.
--------\Cancer
Lists\------------------------------------------------------
---NTP
Carcinogen---
Ingredient
Known Anticipated
IARC Category
------------------------------------
----- ----------- -------------
Propylene Glycol (57-55-6)
No No None
12. Ecological
Information
Environmental Fate:
When released into the soil, this material is expected to readily biodegrade.
When released into the soil, this material is expected to leach into
groundwater. When released into water, this material is expected to readily
biodegrade. When released into the air, this material is expected to be readily
degraded by reaction with photochemically produced
hydroxyl radicals. When released into the air, this material is expected to
have a half-life between 1 and 10 days.
Environmental Toxicity:
No information found.
13. Disposal
Considerations
Whatever cannot be saved for
recovery or recycling should be managed in an appropriate and approved waste
disposal facility. Processing, use or contamination of this product may change
the waste management options. State and local disposal regulations may differ
from federal disposal regulations. Dispose of container and unused contents in
accordance with federal, state and local requirements.
14. Transport
Information
Not regulated.
15. Regulatory
Information
--------\Chemical
Inventory Status - Part 1\---------------------------------
Ingredient
TSCA EC
----------------------------------------------- ----
--- ----- ---------
Propylene
Glycol (57-55-6)
Yes Yes Yes Yes
--------\Chemical Inventory Status - Part
2\---------------------------------
--
Ingredient
----------------------------------------------- -----
--- ---- -----
Propylene Glycol (57-55-6) Yes Yes No
Yes
--------\Federal, State & International Regulations - Part
1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ
List Chemical Catg.
----------------------------------------- ---
----- ---- --------------
Propylene Glycol (57-55-6) No No No No
--------\Federal, State & International Regulations - Part
2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33
8(d)
----------------------------------------- ------
------ ------
Propylene Glycol (57-55-6) No No No
Chemical Weapons Convention: No
TSCA 12(b): No CDTA:
No
SARA 311/312:
Acute: Yes Chronic: No Fire: No
Pressure: No
Reactivity: No (Pure / Liquid)
Australian Hazchem Code: No information found.
Poison Schedule: No information found.
WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled
Products Regulations (CPR) and the MSDS contains all of the information
required by the CPR.
16. Other Information
NFPA Ratings: Health: 0 Flammability: 1 Reactivity: 0
Label Hazard Warning:
CAUTION! MAY CAUSE IRRITATION TO SKIN AND EYES.
Label Precautions:
Avoid contact with eyes, skin and clothing.
Wash thoroughly after handling.
Label First Aid:
In case of contact, immediately flush skin or eyes with plenty of water for at
least 15 minutes. Call a physician if irritation develops or persists.
Product Use:
Laboratory Reagent.
Revision Information:
MSDS Section(s) changed since last revision of document include: 8.
Disclaimer:
************************************************************************************************
Mallinckrodt Baker, Inc. provides the information contained herein in good
faith but makes no representation as to its comprehensiveness or accuracy. This
document is intended only as a guide to the appropriate precautionary handling
of the material by a properly trained person using this product. Individuals
receiving the information must exercise their independent judgment in
determining its appropriateness for a particular purpose. MALLINCKRODT BAKER,
INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED,
INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A
PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE
PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC.
WILL NOT BE RESPONSI
************************************************************************************************
Prepared by: Environmental Health & Safety
Phone Number: (314) 654-1600 (